The incidence of myocarditis was 50.1 to 64.9 cases per 100,000 after infection with the COVID-19 virus among males in this age group.įor the new study, the Yale research team conducted a detailed analysis of immune system responses in those rare cases of myocarditis among vaccinated individuals. The increased incidence of myocarditis during vaccination was seen primarily in males in their teens or early 20s, who had been vaccinated with mRNA vaccines, which are designed to elicit immune responses specifically to the SARS-CoV-2 virus.Īccording to the Centers for Disease Control and Prevention (CDC), among males aged 12 to 17, about 22 to 36 per 100,000 experienced myocarditis within 21 days after receiving a second vaccine dose. Myocarditis is a generally mild inflammation of heart tissue which can cause scarring but is usually resolved within days. These findings, published May 5 in the journal Science Immunology, rule out some of the theorized causes of the heart inflammation and suggest potential ways to further reduce the incidence of a still rare side effect of vaccination, the authors say. In a new study, Yale scientists have identified the immune signature of these heart inflammation cases. It was unclear, however, what exactly was causing this reaction. When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines.
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